VX-809 biochemical product blogThe VX-809 n/a (Catalog #MBS842972) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.
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Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the VX-809 with the following immunoassay(s):
Background: VX-809 is a novel CFTR corrector that modulates the folding and trafficking of CFTR protein. VX-809 stabilizes an N-terminal domain in CFTR that contains only MSD1 (membrane-spanning domain 1) and efficaciously restores function to CFTR forms that have missense mutations in MSD1. The action of VX-809 on MSD1 appears to suppress folding defects in F508del-CFTR by enhancing interactions among the NBD1, MSD1, and MSD2 domains.
CAS Number: 936727-05-8
Structure Available?: Yes
Salt Form: No
PubChem CID: 16678941. Solubility/Reconstitution Instructions: DMSO (>90 mg/ml)
InChi Key: UFSKUSARDNFIRC-UHFFFAOYSA-N
Handling: Protect from air and light.