MK-1439 biochemical product blogThe MK-1439 n/a (Catalog #MBS846392) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.
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Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the MK-1439 with the following immunoassay(s):
MK-1439 (also known as Doravirine); is a non-reversible reverse transcriptase inhibitor used in the treatment of HIV/AIDS with IC50 values of 12; 9.7; and 9.7 nM against the wild type (WT); K103N and Y181C reverse transcriptase (RT) mutants; respectively. It displays excellent activity of suppressing the replication of WT virus with 95% effective concentration of 20 nM. It also exhibited anti-virus activity against 10 different HIV-1 subtype viruses including K103N; Y81C.
Salt Form: No
CAS Number: 1338225-97-0 . Cell-Permeable: Yes
InChi Key: ZIAOVIPSKUPPQW-UHFFFAOYSA-N.