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ABT-888 biochemical product blog

Tags: Biochemical; ABT-888; ABT-888 biochemical;

     The ABT-888 n/a (Catalog #MBS842958) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the ABT-888 with the following immunoassay(s):
Structure
Structure ABT-888.

Background: Potent inhibitor of PARP-1 and PARP-2 (potency <=5 nM in vitro). Does not inhibit other NAD-binding enzymes. Has minimal CYP450 inhibition and induction. Shows broad spectrum of chemo- and radio-potentiation. Does not show inherent cytotoxicity and shows no single agent activity in tumor models.

CAS Number: 912445-05-7
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
MDL Number: MFCD16661206
PubChem CID: 11960529. Solubility/Reconstitution Instructions: DMSO and H?O
SMILES: CC1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N
InChi: InChI=1S/C13H16N4O/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17)/t13-/m1/s1
InChi Key: JNAHVYVRKWKWKQ-CYBMUJFWSA-N
Handling: Protect from air and moisture.
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