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Latest Biochemical blogs from MyBioSource

Z-ATAD-FMK biochemical product blog

Posted on October 8th, 2018 by mybiosource_staff

The Z-ATAD-FMK n/a (Catalog #MBS842069 is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Z-Ala-Thr- Ala-Asp(OM e)-FMK. Background: A synthetic peptide that irreversibly inhibits caspase-12 and related caspase activity. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups). Structure Available?: No Salt Form: No Cell-Permeable?: Yes. Solubility/Reconstitution Instructions: DMSO (20 mM) Handling: Protect from light and...

Leflunomide biochemical product blog

Posted on October 8th, 2018 by mybiosource_staff

The Leflunomide n/a (Catalog #MBS843049 is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. Background: Cell-permeable. An immunosuppressive agent. Inhibits T and B cell responses in vivo. Inhibitor of tyrosine phosphorylation (tyrosine kinase inhibitor), of dihydroorotate dehydrogenase, an enzyme for de novo pyrimidine synthesis, of TNF-dependent NF-kappaB activation, and of COX-2. The physiological activity of leflunomide is attributed mainly to its metabolite A77 1726. CAS Number: 75706-12-6 Structure Available?: Yes Salt Form: No Cell-Permeable?: Yes MDL Number: MFCD00867593 PubChem CID: 3899. Solubil...

Phosphate tris(acetoxymethyl)ester (PO4-AM3) biochemical product blog

Posted on October 8th, 2018 by mybiosource_staff

The Phosphate tris(acetoxymethyl)ester (PO4-AM3) n/a (Catalog #MBS256162 is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. In PO4-AM3three acetoxymethyl (AM) ester groups are connected to inorganic phosphate. Properties: PO4-AM3is a membrane- permeable prodrug of inorganic phosphate. The acetoxymethyl group s mask the charge d polar phosphate and thus render the molecule highly membrane - permeant. Inside the cell esterases release the highly polar inorganic phosphate (PO 4 3 - ). In addition, the AM ester groups liberate acetic aci d and f...
The 2\'- Deoxyguanosine- 5\'- O- (1- thiotriphosphate), Rp- isomer (Rp-dGTP-alpha-S) n/a (Catalog #MBS256319 is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. C10H16N5O12P3S; MW 523.3 (free acid); lambdamax 252 nm; epsilon 14300; sodium salt; purity > 95% HPLC. For other salt forms or a guaranteed higher purity please inquire. Useful for modulation of dGTP-responsive receptors and determination of their stereospecificity. Increased metabolic stability compared to dGTP. Not accepted b...

Ruthenium Red biochemical product blog

Posted on October 8th, 2018 by mybiosource_staff

The Ruthenium Red n/a (Catalog #MBS842547 is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. Background: Ruthenium red is an inhibitor of mitochondrial Ca? uniporter; also blocks cell membrane-located capsaicin-activated cation channels (IC?? = 14 nM) and voltage-sensitive Ca? channels to inhibit neurotransmitter release. In addition, it specifically blocks the curcumin-induced apoptosis in U937 cells. CAS Number: 11103-72-3 Structure Available?: Yes Salt Form: No Cell-Permeable?: No MDL Number: MFCD00011479. Solubility/Reconstitution Instructions: H?O (~8 mg/ml) Handling: Protect from air and light....

Catharanthine biochemical product blog

Posted on October 8th, 2018 by mybiosource_staff

The Catharanthine n/a (Catalog #MBS842730 is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. Background: Catharanthine is one of the alkaloids isolated from the plant Catharanthus roseus. It stimulates the release of amylase from pancreatic fragments and causes extensive degranulation of pancreatic acinar cells with accumulation of membrane material in the Golgi region. It also fully inhibits nicotinic receptor mediated diaphragm contractions (IC?? = 59.6 uM). CAS Number: 2468-21-5 Structure Available?: Yes Salt Form: No Cell-Permeable?: Yes MDL Number: MFCD01753356 PubChem CID: 418553. Solubility/Re...

Elastase Inhibitor, SPCK biochemical product blog

Posted on October 8th, 2018 by mybiosource_staff

The Elastase Inhibitor, SPCK n/a (Catalog #MBS842938 is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. Background: A potent, irreversible inhibitor of human leukocyte elastase (HLE) (Ki = 10 uM). CAS Number: 65144-34-5 Structure Available?: Yes Salt Form: No Cell-Permeable?: No MDL Number: MFCD00077136 PubChem CID: 5486692. Solubility/Reconstitution Instructions: DMSO SMILES: CC(C)C(C(=O)CCl)NC(=O)C1CCCN1C(=O)C(C)NC(=O)C(C)NC(=O)CCC(=O)OC InChi: InChI=1S/C22H35ClN4O7/c1-12(2)19(16(28)11-23)26-21(32)15-7-6-10-27(15)22(33)14(4)25-20(31)13(3)24-17(29)8-9-18(30)34-5/h12-15,19H,6-11H...

Cyanidin 3-Xyloside biochemical product blog

Posted on October 8th, 2018 by mybiosource_staff

The Cyanidin 3-Xyloside n/a (Catalog #MBS6120041 is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. An anthocyanin found in plums and berries which may have an important role in cancer therapy. CAS Number: 29761-24-8 Molecular Formula: C20H19ClO10. Melting Point: >110 degree C (dec.) Solubility: Methanol.

rac 1,2-Dioleoyl-3-chloropropanediol-13C36 biochemical product blog

Posted on October 8th, 2018 by mybiosource_staff

The rac 1,2-Dioleoyl-3-chloropropanediol-13C36 n/a (Catalog #MBS6075383 is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. New lipids in food protein hydrolyzates. Molecular Formula: C313C36H71ClO4. Solubility: Chloroform, Methanol.

3-Bromoaniline biochemical product blog

Posted on October 8th, 2018 by mybiosource_staff

The 3-Bromoaniline n/a (Catalog #MBS6066763 is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. Molecular Formula: C6H6BrN. Solubility: Chloroform.

Piperonyl Butoxide biochemical product blog

Posted on October 8th, 2018 by mybiosource_staff

The Piperonyl Butoxide n/a (Catalog #MBS6083583 is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. Insecticide synergist, especially for pyrethroids and rotenone. Molecular Formula: C19H30O5. Solubility: Benzene, Ethanol, Methanol,.

Z-VDVAD-FMK biochemical product blog

Posted on October 8th, 2018 by mybiosource_staff

The Z-VDVAD-FMK n/a (Catalog #MBS843179 is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Z-Val-Asp( OMe)-Val-A la-Asp(OMe )-FMK. Background: A synthetic peptide that irreversibly inhibits activity of caspase-2. The inhibitor is designed as a methyl ester to facilitate cell permeability. The product can be used for both in vitro and in vivo studies. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups). Structure Available?: No Salt Form: No Cell-Permeable?: Yes MDL Number: MFCD03452881 Pub...
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