XL-147 biochemical product blog
Tags: Biochemical; XL-147; XL-147 biochemical;
The XL-147 n/a (Catalog #MBS842904) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the XL-147 with the following immunoassay(s):
Structure
Background: XL-147 is an ATP-competitive, highly selective, and reversible pan-class I phosphoinositide 3-kinase (PI3K) inhibitor. It inhibits PI3K p110alpha, -beta, -gamma, and -delta isoforms, with IC?? values of 48, 617, 10, and 260 nmol/L, respectively, measured in biochemical assays. XL-147 displays antitumor activity.
CAS Number: 956958-53-5
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
PubChem CID: 56599306. Solubility/Reconstitution Instructions: DMSO (~ 3 mg/ml)
SMILES: CC(C)(C(=O)NC1=CC(=CC=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=C(C=CC(=C4)OC)Cl)N
InChi: InChI=1S/C25H25ClN6O4S/c1-25(2,27)24(33)28-15-7-6-8-17(13-15)37(34,35)32-23-22(29-19-9-4-5-10-20(19)30-23)31-21-14-16(36-3)11-12-18(21)26/h4-14H,27H2,1-3H3,(H,28,33)(H,29,31)(H,30,32)
InChi Key: QINPEPAQOBZPOF-UHFFFAOYSA-N
Handling: Protect from air and light.