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VX-765 biochemical product blog

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Posted on 2015-10-21 07:16:23 by mybiosource_staff
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Tags: Biochemical; VX-765; VX-765 biochemical;
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The VX-765 n/a (Catalog #MBS842656) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the VX-765 with the following immunoassay(s):
Structure
Structure VX-765.

Background: VX-765 is a prodrug of VRT-043198, a potent and selective inhibitor of interleukin-converting enzyme/caspase-1 subfamily caspases. VRT-043198 displays 100- to 10,000-fold selectivity against caspase-3 and -6 to -9. Exhibits potent anti-inflammatory activities by inhibiting the release of IL-1beta and IL-18.

CAS Number: 273404-37-8
Structure Available?: Y
Salt Form: No
Cell-Permeable?: Y
PubChem CID: 11398092. Solubility/Reconstitution Instructions: DMSO (~ 200 mg/ml)
SMILES: CCOC1C(CC(=O)O1)NC(=O)C2CCCN2C(=O)C(C(C)(C)C)NC(=O)C3=CC(=C(C=C3)N)Cl
InChi: InChI=1S/C24H33ClN4O6/c1-5-34-23-16(12-18(30)35-23)27-21(32)17-7-6-10-29(17)22(33)19(24(2,3)4)28-20(31)13-8-9-15(26)14(25)11-13/h8-9,11,16-17,19,23H,5-7,10,12,26H2,1-4H3,(H,27,32)(H,28,31)/t16-,17-,19+,23+/m0/s1
InChi Key: SJDDOCKBXFJEJB-MOKWFATOSA-N
Handling: Protect from air and light.
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