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UNC2881 biochemical product blog

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Posted on 2015-08-17 10:05:18 by mybiosource_staff
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Tags: Biochemical; UNC2881; UNC2881 biochemical;
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The UNC2881 n/a (Catalog #MBS842033) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the UNC2881 with the following immunoassay(s):
Structure
Structure UNC2881.

Background: UNC2881 is a potent Mer kinase inhibitor. It inhibits steady-state Mer kinase phosphorylation with an IC?? value of 22 nM. Treatment with UNC2281 is also sufficient to block EGF-mediated stimulation of a chimeric receptor containing the intracellular domain of Mer fused to the extracellular domain of EGFR.

CAS Number: 1493764-08-1
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
PubChem CID: 71721525. Solubility/Reconstitution Instructions: DMSO
SMILES: CCCCNC1=NC=C(C(=N1)NC2CCC(CC2)O)C(=O)NCC3=CC=C(C=C3)N4C=CN=C4
InChi: InChI=1S/C25H33N7O2/c1-2-3-12-27-25-29-16-22(23(31-25)30-19-6-10-21(33)11-7-19)24(34)28-15-18-4-8-20(9-5-18)32-14-13-26-17-32/h4-5,8-9,13-14,16-17,19,21,33H,2-3,6-7,10-12,15H2,1H3,(H,28,34)(H2,27,29,30,31)
InChi Key: NPVXOWLPOFYACO-UHFFFAOYSA-N
Handling: Protect from air and light.
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