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Torin 1 biochemical product blog

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Posted on 2015-11-11 20:55:51 by mybiosource_staff
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Tags: Biochemical; Torin 1; Torin 1 biochemical;
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The Torin 1 n/a (Catalog #MBS841977) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the EZSolution Torin 1 with the following immunoassay(s):
Structure
Structure Torin 1.

Background: A potent, selective and ATP-competitive mTOR inhibitor, with IC?? values of 2 and 10 nM for mTORC1 and mTORC2 respectively; Torin1 displays 1000-fold selectivity for mTOR over PI3K (EC?? = 1800 nM) and exhibits 100-fold binding selectivity relative to 450 other protein kinases.

CAS Number: 1222998-36-8
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
MDL Number: MFCD18782653
PubChem CID: 49836027. SMILES: CCC(=O)N1CCN(CC1)C2=C(C=C(C=C2)N3C(=O)C=CC4=CN=C5C=CC(=CC5=C43)C6=CC7=CC=CC=C7N=C6)C(F)(F)F
InChi: InChI=1S/C35H28F3N5O2/c1-2-32(44)42-15-13-41(14-16-42)31-11-9-26(19-28(31)35(36,37)38)43-33(45)12-8-24-20-40-30-10-7-22(18-27(30)34(24)43)25-17-23-5-3-4-6-29(23)39-21-25/h3-12,17-21H,2,13-16H2,1H3
InChi Key: AKCRNFFTGXBONI-UHFFFAOYSA-N
Handling: Protect from light and moisture.
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