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TMP269 biochemical product blog

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Posted on 2015-10-03 15:56:22 by mybiosource_staff
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Tags: Biochemical; TMP269; TMP269 biochemical;
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The TMP269 n/a (Catalog #MBS843167) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the TMP269 with the following immunoassay(s):
Structure
Structure TMP269.

Background: TMP269 is a potent, selective and cell-permeable class IIa HDAC inhibitor (IC?? values of of 126 nM, 80 nM, 36 nM and 19 nM for HDAC4, HDAC5, HDAC7 and HDAC9 respectively). Displays 20-400 fold selectivity over class I HDACs.

CAS Number: 1314890-29-3
Structure Available?: Y
Salt Form: No
Cell-Permeable?: Yes. Solubility/Reconstitution Instructions: DMSO (>25 mg/ml)
SMILES: O=C(NCC1(C2=NC(C3=CC=CC=C3)=CS2)CCOCC1)C4=CC=CC(C5=NOC(C(F)(F)F)=N5)=C4
InChi: InChI=1S/C25H21F3N4O3S/c26-25(27,28)22-31-20(32-35-22)17-7-4-8-18(13-17)21(33)29-15-24(9-11-34-12-10-24)23-30-19(14-36-23)16-5-2-1-3-6-16/h1-8,13-14H,9-12,15H2,(H,29,33)
InChi Key: HORXBWNTEDOVKN-UHFFFAOYSA-N
Handling: Protect from air and light.
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