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Smo agonist, SAG dihydrochloride biochemical product blog

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Posted on 2015-08-16 04:55:46 by mybiosource_staff
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Tags: Biochemical; Smo agonist, SAG dihydrochloride; Smo agonist, SAG dihydrochloride biochemical;
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The Smo agonist, SAG dihydrochloride n/a (Catalog #MBS842929) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the Smo agonist, SAG dihydrochloride with the following immunoassay(s):
Structure
Structure Smo agonist, SAG dihydrochloride.

Background: SAG hydrochloride is the water-soluble analog of SAG. A cell-permeable Smoothened (Smo) agonist that has shown to induce Hedgehog pathway activation and counteract cyclopamine inhibition of Smo. SAG has been reported to act as an activator at low concentrations, but can inhibit Smo at very high concentrations.

CAS Number: 364590-63-6
Structure Available?: Y
Salt Form: No
Cell-Permeable?: Y
PubChem CID: 71433770. Solubility/Reconstitution Instructions: H2O (~ 25 mg/ml) DMSO (~ 10 mg/ml)
SMILES: CNC1CCC(CC1)N(CC2=CC=CC(=C2)C3=CC=NC=C3)C(=O)C4=C(C5=CC=CC=C5S4)Cl.O.Cl.Cl
InChi: InChI=1S/C28H28ClN3OS.2ClH.H2O/c1-30-22-9-11-23(12-10-22)32(28(33)27-26(29)24-7-2-3-8-25(24)34-27)18-19-5-4-6-21(17-19)20-13-15-31-16-14-20;;;/h2-8,13-17,22-23,30H,9-12,18H2,1H3;2*1H;1H2
InChi Key: IYXUQUYRWPGIQL-UHFFFAOYSA-N
Handling: Protect from light and moisture.
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