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SD208 biochemical product blog

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Posted on 2016-01-23 20:49:58 by mybiosource_staff
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Tags: Biochemical; SD208; SD208 biochemical;
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The SD208 n/a (Catalog #MBS842038) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the SD208 with the following immunoassay(s):
Structure
Structure SD208.

Background: SD208 is a potent, ATP-competitive transforming growth factor-beta receptor 1 (TGF-betaR1) kinase inhibitor (IC?? = 49 nM). Displays > 100-fold and > 17-fold selectivity over TGF-betaRII and other common kinases respectively. Exhibits anti-inflammatory and antitumor activity.

CAS Number: 627536-09-8
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
MDL Number: MFCD11519969
PubChem CID: 10316032. Solubility/Reconstitution Instructions: DMSO (>5 mg/ml)
SMILES: C1=CC(=C(C=C1Cl)C2=NC3=NC=CN=C3C(=N2)NC4=CC=NC=C4)F
InChi: InChI=1S/C17H10ClFN6/c18-10-1-2-13(19)12(9-10)15-24-16-14(21-7-8-22-16)17(25-15)23-11-3-5-20-6-4-11/h1-9H,(H,20,22,23,24,25)
InChi Key: BERLXWPRSBJFHO-UHFFFAOYSA-N
Handling: Protect from air and light.
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