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S-Adenosyl-L-methionine disulfate tosylate biochemical product blog

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Posted on 2017-05-09 15:27:31 by mybiosource_staff
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Tags: Biochemical; S-Adenosyl-L-methionine disulfate tosylate; S-Adenosyl-L-methionine disulfate tosylate biochemical;
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The S-Adenosyl-L-methionine disulfate tosylate n/a (Catalog #MBS842054) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the S-Adenosyl-L-methionine disulfate tosylate with the following immunoassay(s):
Structure
Structure S-Adenosyl-L-methionine disulfate tosylate.

Background: A methyl donor and a cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. SAM is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinoma (HCC), HepG2 cells and colon cancer cells.

CAS Number: 97540-22-2
Structure Available?: Yes
Cell-Permeable?: No
MDL Number: MFCD01674068
PubChem CID: 163657. Solubility/Reconstitution Instructions: H?O (~100 mg/ml)
SMILES: CC1=CC=C(C=C1)S(=O)(=O)[O-].C[S+](CCC(C(=O)O)N)CC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O.OS(=O)(=O)[O-].[O-]S(=O)(=O)[O-]
InChi: InChI=1S/C15H22N6O5S.C7H8O3S.2H2O4S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21;1-6-2-4-7(5-3-6)11(8,9)10;2*1-5(2,3)4/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25);2-5H,1H3,(H,8,9,10);2*(H2,1,2,3,4)/p-3/t7-,8+,10+,11+,14+,27?;;;/m0../s1
InChi Key: XDCFCHNAIMYBAZ-XQVUROGGSA-K
Handling: Protect from moisture.
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