Remodelin biochemical product blog
Tags: Biochemical; Remodelin; Remodelin biochemical;
The Remodelin n/a (Catalog #MBS842440) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the Remodelin with the following immunoassay(s):
Structure
Background: Remodelin is a potent and selective inhibitor of the acetyl-transferase protein NAT10 that mediates nuclear shape rescue in laminopathic (LMNA-depleted) cells via microtubule reorganization. Remodelin markedly reduces the prevalence of misshapen nuclei in HGPS cells as well as in primary MRC5 fibroblasts aged in culture. In contrast, Remodelin has no effect on nonlaminopathic Werner syndrome cells.
CAS Number: 949912-58-7
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
PubChem CID: 44442376. Solubility/Reconstitution Instructions: DMSO (~ 15 mg/ml)
SMILES: C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)C#N)C1
InChi: InChI=1S/C15H14N4S/c16-9-11-5-7-12(8-6-11)14-10-20-15(17-14)19-18-13-3-1-2-4-13/h5-8,10H,1-4H2,(H,17,19)
InChi Key: XAEJIFARBQJLML-UHFFFAOYSA-N
Handling: Protect from air and light.