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PX 12 biochemical product blog

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Posted on 2015-10-06 16:50:30 by mybiosource_staff
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Tags: Biochemical; PX 12; PX 12 biochemical;
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The PX 12 n/a (Catalog #MBS841915) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the PX 12 with the following immunoassay(s):
Structure
Structure PX 12.

Background: PX-12 is an irreversible inhibitor of thioredoxin-1 (TRX-1) (Ki = 31 uM). It decreases the expression of HIF-1alpha, VEGF and iNOS (IC?? values are 7.2, ~10 and 18.1 muM respectively). Also known to display antitumor activity and inhibits tubulin polymerization in vitro.

CAS Number: 141400-58-0
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
MDL Number: MFCD18086851
PubChem CID: 219104. Solubility/Reconstitution Instructions: DMSO (100 mM)
SMILES: CCC(C)SSC1=NC=CN1
InChi: InChI=1S/C7H12N2S2/c1-3-6(2)10-11-7-8-4-5-9-7/h4-6H,3H2,1-2H3,(H,8,9)
InChi Key: BPBPYQWMFCTCNG-UHFFFAOYSA-N
Handling: Protect from light and moisture.
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