PRIMA-1 biochemical product blog
Tags: Biochemical; PRIMA-1; PRIMA-1 biochemical;
The PRIMA-1 prima1 (Catalog #MBS842987) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.The PRIMA-1 prima1 product has the following accession number(s) (GI #29788778) (NCBI Accession #NP_821092.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the PRIMA-1 with the following immunoassay(s):
Structure
Background: A small molecule that restores tumor suppressor function to mutant p53 proteins. PRIMA-1 acts as an inducer of apoptosis and inhibitor of growth of human tumors with mutant p53. PRIMA-1 restores sequence-specific DNA binding and transactivational activity to mutant p53 proteins at relatively high uM to mM concentrations.
CAS Number: 5608-24-2
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
MDL Number: MFCD04974196
PubChem CID: 322968. Solubility/Reconstitution Instructions: H?O (100 mM)
SMILES: C1CN2CCC1C(=O)C2(CO)CO
InChi: InChI=1S/C9H15NO3/c11-5-9(6-12)8(13)7-1-3-10(9)4-2-7/h7,11-12H,1-6H2
InChi Key: RFBVBRVVOPAAFS-UHFFFAOYSA-N
Handling: Protect from air and moisture. Brain, Liver, Lung, Muscle, Nerve, Prostate tissues are correlated with this protein. Adenocarcinoma, Atherosclerosis, Breast Neoplasms, Chromosome Aberrations, Depressive Disorder, Intestinal Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Experimental are some of the diseases may be linked to PRIMA-1.