PD0332991 biochemical product blog
Tags: Biochemical; PD0332991; PD0332991 biochemical;
The PD0332991 n/a (Catalog #MBS843235) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the PD0332991 with the following immunoassay(s):
Structure
Background: PD0332991 is a highly specific inhibitor of Cdk4 (IC?? = 11 nM) and Cdk6 (IC?? = 16 nM). Displays selectivity for Cdk4/6 over a panel of 34 additional protein kinases (IC??�values are > 10�muM).
CAS Number: 571190-30-2
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
PubChem CID: 5330286. Solubility/Reconstitution Instructions: DMSO
SMILES: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C
InChi: InChI=1S/C24H29N7O2/c1-15-19-14-27-24(28-20-8-7-18(13-26-20)30-11-9-25-10-12-30)29-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32/h7-8,13-14,17,25H,3-6,9-12H2,1-2H3,(H,26,27,28,29)
InChi Key: AHJRHEGDXFFMBM-UHFFFAOYSA-N
Handling: Protect from air and light.