NSC 66811 biochemical product blog
Tags: Biochemical; NSC 66811; NSC 66811 biochemical;
The NSC 66811 n/a (Catalog #MBS843278) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the NSC 66811 with the following immunoassay(s):
Structure
Background: Cell-permeable. Potent MDM2 (murine double minute 2) inhibitor (Ki = 120 nM) that disrupts MDM2-p53 interaction and activates p53 in cancer cells. Induces p21, p53 and MDM2 accumulation in human colon cancer cells in vitro.
CAS Number: 6964-62-1
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
PubChem CID: 248986. Solubility/Reconstitution Instructions: DMSO (~ 100 mM)
SMILES: CC1=NC2=C(C=C1)C=CC(=C2O)C(C3=CC=CC=C3)NC4=CC=CC=C4
InChi: InChI=1S/C23H20N2O/c1-16-12-13-18-14-15-20(23(26)22(18)24-16)21(17-8-4-2-5-9-17)25-19-10-6-3-7-11-19/h2-15,21,25-26H,1H3
InChi Key: WEENRMPCSWFMTE-UHFFFAOYSA-N
Handling: Protect from air and light.