ML-323 biochemical product blog
Tags: Biochemical; ML-323; ML-323 biochemical;
The ML-323 n/a (Catalog #MBS842140) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the ML-323 with the following immunoassay(s):
Structure
Background: ML323 is a potent, reversible, inhibitor of USP1-UAF1 with IC?? of 76 nM in an Ub-Rho assay and 174 nM and 820 nM in orthogonal gel-based assays using K63-linked diubiquitin (di-Ub) and monoubiquitinated PCNA (Ub-PCNA) as substrates, respectively.
CAS Number: 1572414-83-5
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
PubChem CID: 60167849. Solubility/Reconstitution Instructions: DMSO (>50 mg/ml) or EtOH (>25 mg/ml)
SMILES: CC1=CN=C(N=C1NCC2=CC=C(C=C2)N3C=CN=N3)C4=CC=CC=C4C(C)C
InChi: nChI=1S/C23H24N6/c1-16(2)20-6-4-5-7-21(20)23-24-14-17(3)22(27-23)25-15-18-8-10-19(11-9-18)29-13-12-26-28-29/h4-14,16H,15H2,1-3H3,(H,24,25,27)
InChi Key: VUIRVWPJNKZOSS-UHFFFAOYSA-N
Handling: Protect from air and light.