MK-571 biochemical product blog
Tags: Biochemical; MK-571; MK-571 biochemical;
The MK-571 n/a (Catalog #MBS842621) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the MK-571 with the following immunoassay(s):
Structure
Background: MK-571 is a selective, CysLT1�receptor antagonist. It blocks the binding of leukotriene LTD4, but not LTC4, to human and guinea pig lung membranes with Ki�values of 0.22 nM and 2.1 nM, respectively. MK 571 effectively blocks LTD4�activation of recombinant human and murine CysLT1�receptors�but is ineffective at blocking LTC4�or LTD4activation of the recombinant human or murine CysLT2�receptors. MK-57 also acts as a specific inhibitor of multi-drug resistance protein-1 (MRP1).
CAS Number: 115104-28-4
Structure Available?: Y
Salt Form: No
Cell-Permeable?: Yes
PubChem CID: �5281888. Solubility/Reconstitution Instructions: DMSO (~40 mg/ml)
SMILES: �CN(C)C(=O)CCSC(C1=CC=CC(=C1)C=CC2=NC3=C(C=CC(=C3)Cl)C=C2)SCCC(=O)O
InChi: �InChI=1S/C26H27ClN2O3S2/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32)/b10-6+
InChi Key: AXUZQJFHDNNPFG-UXBLZVDNSA-N
Handling: Protect from air and light.