MIF antagonist, p425 biochemical product blog
Tags: Biochemical; MIF antagonist, p425; MIF antagonist, p425 biochemical;
The MIF antagonist, p425 n/a (Catalog #MBS842281) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the MIF antagonist, p425 with the following immunoassay(s):
Structure
Background: A counterstain for background autofluorescence in fluorescence and immunofluorescence histochemistry. Acts as an allosteric MIF (macrophage migration inhibitory factor) inhibitor. It occupies an interface of MIF trimers, leading to the loss of its tautomerase, receptor binding, and pro-inflammatory activities. An excellent tool to design MIF-directed therapeutics for inflammatory diseases.
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: No
MDL Number: MFCD00004020
PubChem CID: 5359775. Solubility/Reconstitution Instructions: H?O (10 mg/ml)
SMILES: COC1=C(C=CC(=C1)C2=CC(=C(C=C2)NN=C3C=CC4=C(C3=O)C(=C(C=C4S(=O)(=O)[O-])S(=O)(=O)[O-])N)OC)NN=C5C=CC6=C(C5=O)C(=C(C=C6S(=O)(=O)[O-])S(=O)(=O)[O-])N.[Na+].[Na+].[Na+].[Na+]
InChi: InChI=1S/C34H28N6O16S4.4Na/c1-55-23-11-15(3-7-19(23)37-39-21-9-5-17-25(57(43,44)45)13-27(59(49,50)51)31(35)29(17)33(21)41)16-4-8-20(24(12-16)56-2)38-40-22-10-6-18-26(58(46,47)48)14-28(60(52,53)54)32(36)30(18)34(22)42;;;;/h3-14,37-38H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4/b39-21-,40-22+;;;;
InChi Key: UPKAWFACSJWKND-ZXFFUEEESA-J
Handling: Protect from air and light.