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LY2886721 biochemical product blog

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Posted on 2015-08-19 16:43:45 by mybiosource_staff
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Tags: Biochemical; LY2886721; LY2886721 biochemical;
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The LY2886721 n/a (Catalog #MBS841964) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the LY2886721 with the following immunoassay(s):
Structure
Structure LY2886721.

Background: Cell-permeable. A potent and selective beta-secretase (BACE-1) inhibitor (IC?? = 20 nM for recombinant hBACE1). Does not inhibit other aspartyl proteases such as cathepsin D, pepsin, and renin. A potential agent to treat Alzheimer\'s Disease.

CAS Number: 1262036-50-9
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
PubChem CID: 49837968. Solubility/Reconstitution Instructions: DMSO (~10 mg/ml) or Ethanol (<1 mg/ml)
SMILES: C1C2CSC(=NC2(CO1)C3=C(C=CC(=C3)NC(=O)C4=NC=C(C=C4)F)F)N
InChi: InChI=1S/C18H16F2N4O2S/c19-11-1-4-15(22-6-11)16(25)23-12-2-3-14(20)13(5-12)18-9-26-7-10(18)8-27-17(21)24-18/h1-6,10H,7-9H2,(H2,21,24)(H,23,25)/t10-,18-/m0/s1
InChi Key: NIDRNVHMMDAAIK-YPMLDQLKSA-N
Handling: Protect from air and light.
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