Ingenol biochemical product blog
Tags: Biochemical; Ingenol; Ingenol biochemical;
The Ingenol n/a (Catalog #MBS842502) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the Ingenol with the following immunoassay(s):
Structure
Background: Ingenol is a diterpenoid related to phorbol that acts as a weak protein kinase C (PKC) activator that displays a Ki value of 30 muM and an ED?? value of 27 muM in vitro. Most ingenol esters are tumor-promoting. However, ingenol mebutate possesses anti-tumor activity when used topically for actinic keratosis.
CAS Number: 30220-46-3
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
MDL Number: MFCD00056380
PubChem CID: 442042. Solubility/Reconstitution Instructions: DMSO or EtOH
SMILES: CC1CC2C(C2(C)C)C3C=C(C(C4(C1(C3=O)C=C(C4O)C)O)O)CO
InChi: InChI=1S/C20H28O5/c1-9-7-19-10(2)5-13-14(18(13,3)4)12(17(19)24)6-11(8-21)16(23)20(19,25)15(9)22/h6-7,10,12-16,21-23,25H,5,8H2,1-4H3/t10-,12+,13-,14+,15+,16-,19+,20-/m1/s1
InChi Key: EBVPUXQAPLADL-POYOOMFHSA-N
Handling: Protect from air and light.