I-BET762 biochemical product blog
Tags: Biochemical; I-BET762; I-BET762 biochemical;
The I-BET762 n/a (Catalog #MBS842743) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the I-BET762 with the following immunoassay(s):
Structure
Background: I-BET762 (GSK525762) is a highly potent, selective and cell-permeable inhibitor of the bromodomain and extra terminal (BET) family protein BRD4 (IC??�of ~35 nM). It inhibits myeloma cell proliferation and suppresses the production of proinflammatory proteins by macrophages and blocks acute inflammation.
CAS Number: 1260907-17-2
Structure Available?: Y
Salt Form: No
Cell-Permeable?: Yes
PubChem CID: 46943432. Solubility/Reconstitution Instructions: DMSO or EtOH
SMILES: �CCNC(=O)CC1C2=NN=C(N2C3=C(C=C(C=C3)OC)C(=N1)C4=CC=C(C=C4)Cl)C
InChi: nChI=1S/C22H22ClN5O2/c1-4-24-20(29)12-18-22-27-26-13(2)28(22)19-10-9-16(30-3)11-17(19)21(25-18)14-5-7-15(23)8-6-14/h5-11,18H,4,12H2,1-3H3,(H,24,29)/t18-/m0/s1
InChi Key: AAAQFGUYHFJNHI-SFHVURJKSA-N
Handling: Protect from air and light.