|The HC Toxin n/a (Catalog #MBS842318) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.
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Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the HC Toxin with the following immunoassay(s):
Background: HC Toxin is a cyclic tetrapeptide first isolated from H. carbonum (now C. carbonum), a pathogen of maize. It is a reversible inhibitor of histone deacetylases (HDACs) (IC?? = 30 nM). Through its effects on HDACs, HC toxin has been shown to up-regulate the expression of 15-lipoxygenase-1 in colorectal cancer cells and induce fetal hemoglobin in human primary erythroid cells.
CAS Number: 83209-65-8
Structure Available?: Y
Salt Form: No
MDL Number: MFCD00133388
PubChem CID: 23724535. Solubility/Reconstitution Instructions: DMSO
InChi Key: GNYCTMYOHGBSBI-KVUCBBCISA-N
Handling: Protect from air and light.