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hbmRI biochemical product blog

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Posted on 2016-01-24 18:24:41 by mybiosource_staff
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Tags: Biochemical; Herbimycin A; hbmRI biochemical; hbmRI;
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The Herbimycin A hbmri (Catalog #MBS842383) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

The Herbimycin A hbmri product has the following accession number(s) (GI #63033864) (NCBI Accession #AAY28238.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the Herbimycin A with the following immunoassay(s):
Structure
Structure Herbimycin A.

Background: Herbimycin An is an ansamycin antibiotic isolated from Streptomyces sp. Inhibits HSP90 and associated client proteins including v-Src, Bcr-Abl, Raf-1 and ErbB2. Herbimycin A reverts tyrosine kinase-induced oncogenic transformation without direct inhibition of phosphorylation activity. It also inhibits angiogenesis in a rat retinopathy model.

CAS Number: 70563-58-5
Structure Available?: Y
Salt Form: No
Cell-Permeable?: Yes
MDL Number: MFCD00151702
PubChem CID: 6436247. Solubility/Reconstitution Instructions: DMSO (~ 6 mg/ml)
SMILES: CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C=C(C1OC)C2=O)C)OC)OC(=O)N)C)C)OC)OC
InChi: InChI=1S/C30H42N2O9/c1-16-10-9-11-23(37-5)28(41-30(31)36)18(3)12-17(2)27(40-8)24(38-6)13-19(4)26(39-7)21-14-20(33)15-22(25(21)34)32-29(16)35/h9-12,14-15,17,19,23-24,26-28H,13H2,1-8H3,(H2,31,36)(H,32,35)/b11-9+,16-10+,18-12+/t17-,19-,23-,24-,26+,27+,28-/m0/s1
InChi Key: MCAHMSDENAOJFZ-GDYSMBPZSA-N
Handling: Protect from air and light.
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