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Guanosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester (cGMP-AM) biochemical product blog

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Posted on 2018-01-09 08:10:58 by mybiosource_staff
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Tags: Biochemical; Guanosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester (cGMP-AM); Guanosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester (cGMP-AM) biochemical;
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The Guanosine- 3\', 5\'- cyclic monophosphate, acetoxymethyl ester (cGMP-AM) n/a (Catalog #MBS256335) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the Guanosine- 3\', 5\'- cyclic monophosphate, acetoxymethyl ester (cGMP-AM) with the following immunoassay(s):
Structure
Structure Guanosine- 3\', 5\'- cyclic monophosphate, acetoxymethyl ester (cGMP-AM).

C13H16N5O9P; MW 417.3; lambdamax 252 nm; epsilon 13500; purity > 95% HPLC for mixture isomers.

Membrane-permeant precursor of the second messenger cyclic GMP. Metabolic activation by esterases releases the polar active analogue which is trapped inside the cell. In contrast to other membrane-permeant and PDE-resistant cGMP analogues, cGMP-AM yields a transient increase (pulse) of cGMP. Especially suitable for external triggering of cGMP-regulated phosphodiesterases (PDE II, III & V) where most cGMP analogues are not accepted. Detailed technical information available. Reference: Schwede et al., Bioorg. Med. Chem. Lett., 10, 571 - 573 (2000).

Unit Equivalent: 1 umol is approximately equals to 0.4 mg
CAS No.: 164007-71-0. Formula: C13H16N5O9P.
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