|The GSK-3 Inhibitor, AR-A014418 n/a (Catalog #MBS842513) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.
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Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the GSK-3 Inhibitor, AR-A014418 with the following immunoassay(s):
Background: Cell-permeable. A selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC?? = 104 nM). Inhibition is competitive with respect to ATP (Ki = 38nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC?? values are > 100 muM) and over 26 other kinases. Inhibits beta-amyloid-mediated neurodegeneration in hippocampal slices.
CAS Number: 487021-52-3
Structure Available?: Yes
Salt Form: No
MDL Number: MFCD08277040
PubChem CID: 448014. Solubility/Reconstitution Instructions: DMSO (30 mg/ml)
InChi Key: YAEMHJKFIIIULI-UHFFFAOYSA-N
Handling: Protect from light and air.