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GSK-3 Inhibitor, AR-A014418 biochemical product blog

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Posted on 2016-01-25 04:25:06 by mybiosource_staff
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Tags: Biochemical; GSK-3 Inhibitor, AR-A014418; GSK-3 Inhibitor, AR-A014418 biochemical;
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The GSK-3 Inhibitor, AR-A014418 n/a (Catalog #MBS842513) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the GSK-3 Inhibitor, AR-A014418 with the following immunoassay(s):
Structure
Structure GSK-3 Inhibitor, AR-A014418.

Background: Cell-permeable. A selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC?? = 104 nM). Inhibition is competitive with respect to ATP (Ki = 38nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC?? values are > 100 muM) and over 26 other kinases. Inhibits beta-amyloid-mediated neurodegeneration in hippocampal slices.

CAS Number: 487021-52-3
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
MDL Number: MFCD08277040
PubChem CID: 448014. Solubility/Reconstitution Instructions: DMSO (30 mg/ml)
SMILES: COC1=CC=C(C=C1)CNC(=O)NC2=NC=C(S2)[N+](=O)[O-]
InChi: InChI=1S/C12H12N4O4S/c1-20-9-4-2-8(3-5-9)6-13-11(17)15-12-14-7-10(21-12)16(18)19/h2-5,7H,6H2,1H3,(H2,13,14,15,17)
InChi Key: YAEMHJKFIIIULI-UHFFFAOYSA-N
Handling: Protect from light and air.
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