|The Garcinol n/a (Catalog #MBS842692) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.
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Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the Garcinol with the following immunoassay(s):
Background: Garcinol is a polyisoprenylated benzophenone derivative isolated from Garcinia indica. It is a potent inhibitor of histone acetyltransferases (HATs) p300 (IC50 = 7 uM) and PCAF (IC50 = 5 uM) both in vitro and in vivo. HAT activity-dependent chromatin transcription was inhibited by garcinol, but it had no effect on naked DNA transcription. Moreover, it induces apoptosis in several types of cancer cells and has anti-inflammatory actions. Garcinol promotes neurogenesis and ex vivo expansion of human hematopoietic stem cells.
CAS Number: 78824-30-3
Structure Available?: Yes
MDL Number: MFCD03700761
PubChem CID: 3531. Solubility/Reconstitution Instructions: DMSO (25 mg/ml) or EtOH (25 mg/ml)
InChi Key: DTTONLKLWRTCAB-UHFFFAOYSA-N
Handling: Protect from air and light.