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DMH-1 biochemical product blog

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Posted on 2018-02-09 17:18:16 by mybiosource_staff
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Tags: Biochemical; DMH-1; DMH-1 biochemical;
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The DMH-1 n/a (Catalog #MBS845724) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the DMH-1 with the following immunoassay(s):
Structure
Structure DMH-1.

DMH-1 is an analog of Dorsomorphin that acts as a highly selective Bone morphogenetic protein (BMP) inhibitor. DMH-1 exclusively targets the BMP but not the VEGF pathway. Blocks BMP4-induced phosphorylation of Smads 1; 5 and 8 in HEK293 cells. Promotes neurogenesis in human induced pluripotent stem cells (iPSCs) when used in combination with SB-431542.

Salt Form: No
Molecular Formula: C24H20N4O
CAS Number: 1206711-16-1. Cell-Permeable: Yes
Reconstitution: DMSO (>5 mg/ml)
SMILES: CC(C)OC1=CC=C(C=C1)C2=CN3C(=C(C=N3)C4=CC=NC5=CC=CC=C45)N=C2
InChi: InChI=1S/C24H20N4O/c1-16(2)29-19-9-7-17(8-10-19)18-13-26-24-22(14-27-28(24)15-18)20-11-12-25-23-6-4-3-5-21(20)23/h3-16H,1-2H3
InChi Key: JMIFGARJSWXZSH-UHFFFAOYSA-N.
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