Cyclopamine-KAAD biochemical product blog
Tags: Biochemical; Cyclopamine-KAAD; Cyclopamine-KAAD biochemical;
The Cyclopamine-KAAD n/a (Catalog #MBS842841) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the Cyclopamine-KAAD with the following immunoassay(s):
Structure
Background: Cell-permeable. A synthetic derivative of the natural product Cyclopamine that acts as a specific inhibitor of Smoothened (Smo) and Sonic hedgehog (Shh) intracellular signaling (IC???=?20 nM in the Shh-LIGHT2 assay).
CAS Number: 306387-90-6
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
MDL Number: MFCD03425585
PubChem CID: 16760383. Solubility/Reconstitution Instructions: DMSO or EtOH
SMILES: CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(=O)CCC6(C5CC4=C3C)C)C)N(C1)CCNC(=O)CCCCCNC(=O)CCC7=CC=CC=C7
InChi: InChI=1S/C44H63N3O4/c1-29-25-39-42(47(28-29)24-23-46-40(49)13-9-6-10-22-45-41(50)17-14-32-11-7-5-8-12-32)31(3)44(51-39)21-19-35-36-16-15-33-26-34(48)18-20-43(33,4)38(36)27-37(35)30(44)2/h5,7-8,11-12,15,29,31,35-36,38-39,42H,6,9-10,13-14,16-28H2,1-4H3,(H,45,50)(H,46,49)/t29?,31-,35?,36?,38?,39-,42?,43?,44?/m1/s1
InChi Key: WDHRPWOAMDJICD-BWBMXWGBSA-N
Handling: Protect from air and moisture.