Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Biochemical Blog  rightarrow Chk2 Inhibitor biochemical  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
separator
 • N6- (6- [N- Methylanthraniloyl]hexylamino)adenosine-3', 5'- cyclic monophosphate (6-MAH-cAMP) biochemical blog
 • 4-Pyridylthioacetic Acid biochemical blog
 • Antipain dihydrochloride biochemical blog
 • Xylene biochemical blog
 • Benzocaine Methanethiosulfonate biochemical blog
 • 3-Butynyl Methanethiosulfonate biochemical blog
 • N-[4-(3,4-Dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenylidene]-2-methyl-2-propanesulfinamide biochemical blog
 • Megestrol biochemical blog
 • 7a-Hydroxycholesterol-d7 biochemical blog
 • Dabigatran-d3 Ethyl Ester biochemical blog
 • 1,3-Dichloroacetone Ethylene Ketal biochemical blog
 • Dibucaine Hydrochloride biochemical blog
 • S-(5'-Adenosyl)-L-homocysteine biochemical blog
 • (2S)-3-Azido-2-hydroxy-2-methyl-propanoic Acid Methyl Ester biochemical blog
 • SAR-260301 biochemical blog
 • 4-[4-(Diphenylmethoxy)-1-piperidinyl]-1-[4-[(2-hydroxy-1,1-dimethyl)ethyl]phenyl]butyne biochemical blog
 • N,N'-Diacetylchitobiose biochemical blog
 • Creatinine biochemical blog
 • 1,6-Di-O-acetyl-2,3,4-tri-O-benzyl-a,b-D-glucopyranose biochemical blog
 • (Z)-4-Hydroxy Tamoxifen O- beta-D-Glucuronide biochemical blog
separator
Blog Categories separator
separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
separator
Our Best Sellers moreseparator
separator
 • RSU1 Antibody
 • Lipid Quantitation Kit
 • LIM Domain Kinase 1-2 (LIMK1) Antibody
 • Tau Antibody
 • SLPI Antibody
 • PRMT2 Antibody
 • LYAR Antibody
 • IL-6 (Il6) Antibody
 • ADORA2a ELISA Kit
 • Troponin T-Cardiac (Tnnt2) Antibody
 • TRAIP cDNA Clone
 • Melanotan-I (MT I) Native Protein
 • Myosin Light Chain Kinase (MYLK) ELISA Kit
 • Mannheimia haemolytica Leukotoxin (lktA) Antibody
 downarrow more ...
separator

Chk2 Inhibitor biochemical product blog

separator
Posted on 2015-09-18 09:24:16 by mybiosource_staff
Share it on ...     
separator
separator
Tags: Biochemical; Chk2 Inhibitor; Chk2 Inhibitor biochemical;
separator
The Chk2 Inhibitor n/a (Catalog #MBS841968) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the Chk2 Inhibitor with the following immunoassay(s):
Structure
Structure Chk2 Inhibitor.

Background: A cell-permeable, potent, and ATP-competitive inhibitor of Chk2 (checkpoint kinase 2; IC?? = 15 nM; Ki = 37 nM). Displays ~1,000-fold greater selectivity for Chk2 compared to Cdk1/cyclin B and CK1 (IC?? = 12 uM and 17 uM, respectively) and only weakly affects the activities of a panel of 31 kinases (< 25% inhibition at 10 uM), including Chk1. Shown to rescue both peripheral CD4+ and CD8+ T-cells from gamma-irradiation-induced apoptosis with an EC?? of 3 uM and 7.6 uM, respectively.

CAS Number: 516480-79-8
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
MDL Number: MFCD08276917
PubChem CID: 9969021. Solubility/Reconstitution Instructions: DMSO (10 mg/ml)
SMILES: C1=CC(=CC=C1C2=NC3=C(N2)C=C(C=C3)C(=O)N)OC4=CC=C(C=C4)Cl
InChi: InChI=1S/C20H14ClN3O2/c21-14-4-8-16(9-5-14)26-15-6-1-12(2-7-15)20-23-17-10-3-13(19(22)25)11-18(17)24-20/h1-11H,(H2,22,25)(H,23,24)
InChi Key: UXGJAOIJSROTTN-UHFFFAOYSA-N
Handling: Protect from air and moisture.
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions