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C646, p300/CBP Inhibitor biochemical product blog

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Posted on 2017-09-09 12:00:51 by mybiosource_staff
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Tags: Biochemical; C646, p300/CBP Inhibitor; C646, p300/CBP Inhibitor biochemical;
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The C646, p300/CBP Inhibitor n/a (Catalog #MBS843084) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the C646, p300 / CBP Inhibitor with the following immunoassay(s):
Structure
Structure C646, p300/CBP Inhibitor.

Background: Cell-permeable. A reversible, p300/CBP (CREB-binding protein) histone acetyltransferase (HAT) inhibitor (Ki = 400 nM). Specific inhibition to p300 (86%) compared to N-acetyltransferase, PCAF, GCN5, Rtt109, Sas or MOZ histone acetyltransferases (<10%). Suppresses histone H3 and H4 acetylation in mouse fibroblast cell lines.

CAS Number: 328968-36-1
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
MDL Number: MFCD01784780
PubChem CID: 1285941. Solubility/Reconstitution Instructions: DMSO (25 mM)
SMILES: CC1=C(C=C(C(=C1)C2=CC=C(O2)C=C3C(=NN(C3=O)C4=CC=C(C=C4)C(=O)O)C)[N+](=O)[O-])C
InChi: InChI=1S/C24H19N3O6/c1-13-10-20(21(27(31)32)11-14(13)2)22-9-8-18(33-22)12-19-15(3)25-26(23(19)28)17-6-4-16(5-7-17)24(29)30/h4-12H,1-3H3,(H,29,30)/b19-12-
InChi Key: HEKJYZZSCQBJGB-UNOMPAQXSA-N
Handling: Protect from light and air.
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