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Bortezomib, Free Base biochemical product blog

Posted on 2015-12-06 09:53:54 by mybiosource_staff
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Tags: Biochemical; Bortezomib, Free Base; Bortezomib, Free Base biochemical;
The Bortezomib, Free Base n/a (Catalog #MBS6068966) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Bortezomib is the active ingredient in the drug sold under the trade name Velcade®. This drug has been approved in at least one country to treat multiple myeloma. It is a potent (Ki, 0.6nM), specific and reversible proteasome inhibitor. There is not any significant inhibitory activity against other enzymes or receptors. In a study with the National Cancer Institute\'s panel of 60 human cell lines, Bortezomib showed a mean IC50 of 7nM as tested by SRB analysis.

Bortezomib, Free Base n/a

CAS Number: 179324-69-7
Molecular Formula: C19H25BN4O4. Melting Point: As reported
Solubility: Soluble in DMSO at 200mg/ml. Soluble in ethanol at 200mg/ml. Very poorly soluble in water. Maximum solubility in plain water is estimated to be about 5-10uM.
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