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BMS-754807 biochemical product blog

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Posted on 2015-08-20 22:02:32 by mybiosource_staff
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Tags: Biochemical; BMS-754807; BMS-754807 biochemical;
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The BMS-754807 n/a (Catalog #MBS842216) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the BMS-754807 with the following immunoassay(s):
Structure
Structure BMS-754807.

Background: BMS-754807 is a potent and reversible inhibitor of the insulin-like growth factor 1 receptor/insulin receptor (IGF-1R/IR) family kinases (Ki, <2 nmol/L). BMS-754807 effectively inhibits the growth of a broad range of human tumor types in vitro, including mesenchymal, epithelial, and hematopoietic tumor cell lines (IC??, 5-365 nmol/L).

CAS Number: 1001350-96-4
Structure Available?: Y
Salt Form: No
Cell-Permeable?: Yes
PubChem CID: 24785538. Solubility/Reconstitution Instructions: DMSO
SMILES: CC1(CCCN1C2=NN3C=CC=C3C(=N2)NC4=NNC(=C4)C5CC5)C(=O)NC6=CN=C(C=C6)F
InChi:  InChI=1S/C23H24FN9O/c1-23(21(34)26-15-7-8-18(24)25-13-15)9-3-10-32(23)22-28-20(17-4-2-11-33(17)31-22)27-19-12-16(29-30-19)14-5-6-14/h2,4,7-8,11-14H,3,5-6,9-10H2,1H3,(H,26,34)(H2,27,28,29,30,31)/t23-/m0/s1
InChi Key: LQVXSNNAFNGRAH-QHCPKHFHSA-N
Handling: Protect from air and light.
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