Auranofin biochemical product blog
Tags: Biochemical; Auranofin; Auranofin biochemical;
The Auranofin n/a (Catalog #MBS842238) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the Auranofin with the following immunoassay(s):
Structure
Background: An anti-arthritic drug that inhibits various leukocyte activation pathways at multiple sites. Inhibits release of inflammatory mediators from human basophils, pulmonary mast cells and macrophages. Also inhibits human neutrophil 5-lipoxygenase. Inhibits IkappaB kinase (IKK) by modifying Cys179 of the IKKbeta subunit. Efficient inducer of mitochondrial membrane permeability transition via the inhibition of mitochondrial thioredoxin reductase (TrxR).
CAS Number: 34031-32-8
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
MDL Number: MFCD00080759
PubChem CID: 24199313. Solubility/Reconstitution Instructions: DMSO (100 mM) or Ethanol (50 mM)
SMILES: CCP(CC)CC.CC(=O)OCC1C(C(C(C(O1)[S-])OC(=O)C)OC(=O)C)OC(=O)C.[Au+]
InChi: InChI=1S/C14H20O9S.C6H15P.Au/c1-6(15)19-5-10-11(20-7(2)16)12(21-8(3)17)13(14(24)23-10)22-9(4)18;1-4-7(5-2)6-3;/h10-14,24H,5H2,1-4H3;4-6H2,1-3H3;/q;;+1/p-1
InChi Key: AUJRCFUBUPVWSZ-UHFFFAOYSA-M
Handling: Protect from light and moisture.