AT9283 biochemical product blog
Tags: Biochemical; AT9283; AT9283 biochemical;
The AT9283 n/a (Catalog #MBS842122) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the AT9283 with the following immunoassay(s):
Structure
Background: A pan-Aurora kinase inhibitor (IC?? = 3 nM for both Aurora An and B). AT9283 also potently inhibits several kinases including the JAK2 and 3 (IC??\'s 1.2 and 1.1 nM, respectively), c-Abl(IC?? = 110 nM) and Abl/T315I (IC?? = 4 nM).
CAS Number: 896466-04-9
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes
PubChem CID: 11696609. Solubility/Reconstitution Instructions: DMSO (>70 mg/ml) or EtOH (>25 mg/ml)
SMILES: C1CC1NC(=O)NC2=CNNC2=C3N=C4C=CC(=CC4=N3)CN5CCOCC5
InChi: InChI=1S/C19H23N7O2/c27-19(21-13-2-3-13)24-16-10-20-25-17(16)18-22-14-4-1-12(9-15(14)23-18)11-26-5-7-28-8-6-26/h1,4,9-10,13,20,25H,2-3,5-8,11H2,(H2,21,24,27)/b18-17-
InChi Key: VRXXZJLHPWWXIX-ZCXUNETKSA-N
Handling: Protect from light and air.