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A-366 biochemical product blog

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Posted on 2015-10-27 14:48:29 by mybiosource_staff
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Tags: Biochemical; A-366; A-366 biochemical;
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The A-366 n/a (Catalog #MBS842453) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the A-366 with the following immunoassay(s):
Structure
Structure A-366.

Background: A-366 is a potent and selective G9a/GLP histone lysine methyltransferase inhibitor (IC?? = 3.3 nM). It displays >1000-fold selectivity for G9a/GLP over 21 other methyltransferases. A-366 has been shown to inhibit H3K9 methylation in prostate cancer PC3 cells with an IC?? of 100 nM.

CAS Number: 1527503-11-2
Structure Available?: Yes
Salt Form: No
Cell-Permeable?: Yes. Solubility/Reconstitution Instructions: DMSO (>25 mg/ml)
SMILES: NC(C12CCC1)=NC3=C2C=C(OC)C(OCCCN4CCCC4)=C3
InChi: InChI=1S/C19H27N3O2/c1-23-16-12-14-15(21-18(20)19(14)6-4-7-19)13-17(16)24-11-5-10-22-8-2-3-9-22/h12-13H,2-11H2,1H3,(H2,20,21)
InChi Key: BKCDJTRMYWSXMC-UHFFFAOYSA-N
Handling: Protect from air and light.
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