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8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel (Sp-8-AEA-cAMPS-Agarose) biochemical product blog

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Posted on 2015-09-24 21:44:21 by mybiosource_staff
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The 8- (2- Aminoethylamino)adenosine- 3\', 5\'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel (Sp-8-AEA-cAMPS-Agarose) n/a (Catalog #MBS256066) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the 8- (2- Aminoethylamino)adenosine- 3\', 5\'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel (Sp-8-AEA-cAMPS-Agarose) with the following immunoassay(s):
Structure
Structure 8- (2- Aminoethylamino)adenosine- 3\', 5\'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel (Sp-8-AEA-cAMPS-Agarose).

The protein kinase An activator Sp-cAMPS immobilized on agarose by an aminoethylamino spacer attached to position 8 of the ligand. Free Sp-cAMPS is only very slowly metabolized by mammalian phosphodiesterases and thus represents an extraordinary stable ligand. In addition, its reduced binding affinity towards protein kinase A compared to cAMP results in milder desorption conditions during affinity chromatography. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. This ligand is offered with a longer spacer (Sp-8-AHA-cAMPS-Agarose) as well. Detailed technical information available. Reference: Bertinetti et al., BMC Chem. Biol, 9 (2009).

Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request..

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