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2'- O- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel (Sp-2'-AHC-cGMPS-Agarose) biochemical product blog

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Posted on 2015-10-23 03:36:21 by mybiosource_staff
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The 2\'- O- (6- Aminohexylcarbamoyl)guanosine- 3\', 5\'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel (Sp-2\'-AHC-cGMPS-Agarose) n/a (Catalog #MBS256365) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given biochemical. We\'ve tested the 2\'- O- (6- Aminohexylcarbamoyl)guanosine- 3\', 5\'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel (Sp-2\'-AHC-cGMPS-Agarose) with the following immunoassay(s):
Structure
Structure 2\'- O- (6- Aminohexylcarbamoyl)guanosine- 3\', 5\'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel (Sp-2\'-AHC-cGMPS-Agarose).

The PDE-resistant PKG activator Sp-cGMPS immobilized on agarose by an aminohexylcarbamoyl spacer attached to the ribose 2\'-position of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins, especially those which tolerate modification of the 2\'-ribose hydroxyl group such as some phosphodiesterases. This type of gel is also offered with normal cGMP (2\'-AHC-cGMP-Agarose). Detailed technical information available. Compare: Corrie et al., Prot. Expr. Purif., 3, 417 - 420 (1992).

Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request..

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